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Combined Detection Of Tumor Markers And Ctdna In Cerebrospinal Fluid: A Good Strategy In Diagnosis Of Leptomeningeal Metastases

Y. Wang, R. Tao

ANNALS OF ONCOLOGY（2021）

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Abstract
The main purpose is to select a more effective method for the diagnosis of leptomeningeal metastases (LM) by comparing various detection methods. The secondary purpose is to identify specific mutation patterns of genes in cerebrospinal fluid (CSF) with LM and to explore the value of CSF tumor markers and circulating tumor DNA (ctDNA) testing in guiding clinical treatment.
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Key words
tumor markers,cerebrospinal fluid,ctdna,1265p combined detection
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