84P Metastatic mismatch repair deficiency cancers: Hard to find, but a delight to treat!

A. Rauthan, N. Y. Murthy,P. Patil,S. Sampige Prasannakumar,S. Zaveri, G. R. Nigade, P. Vundemodalu, R. Ashwath, C. Jomi

Annals of Oncology(2021)

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摘要
Metastatic cancers with mismatch repair (MMR) deficiency, seen especially in cancers of the uterus and gastrointestinal tract, are rare and seen in about 5% of patients. They show very good and durable response to treatment with immunotherapy, leading to a tumor agnostic approval in this indication. There is very limited data of MMR deficient patients treated with immunotherapy from India.
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deficiency,repair
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