The effects of SNAI1 rs6125849 gene polymorphism on metastasis and survival in colorectal cancer: Preliminary results from Turkish subjects

•SNAI1 involves in many carcinogenic processes and has been considered as a new therapeutic target.•Since SNAI1 is crucial in carcinogenesis, the effects of SNAI1 gene variations on oncogenic processes have become important in recent years.•In the present study, we investigated the effects of SNAI1 rs6125849 G>A variation on several features of colorectal cancer (CRC).•According to our results, rs6125849 variation might have an effect on metastasis and patients survival but not CRC risk and primary tumor location.•Further in vitro and in vivo studies are necessary to validate our results and understand the function of rs6125849 polymorphism.