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3D printed porous microgel for lung cancer cells culture in vitro

Qipeng Hu,Xuan Liu,Haofan Liu,Ling Yang,Xin Yuan,Yuwen Chen,Wenbi Wu,Jing Luo,Jianlin Long,Meijuan Huang,Maling Gou

Materials & Design（2021）

Cited 9|Views10
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Abstract
•A novel method for 3D lung cancer cell culture via 3D printed porous microgel.•The ROCK pathway in 3D cultured lung cancer cells is similar to the solid tumors.•Overexpression of the ROCK pathway enhances paclitaxel resistance in lung cancers.
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Key words
DLP 3D bioprinting,3D cell culture,Microgels,Lung cancer,Cytoskeleton,Rho-associated kinase protein-1 inhibitor
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