Electricity-induced micro-flow C-H/N-H alkyne annulation: a greener approach to access heteroaromatic compounds
REACTION CHEMISTRY & ENGINEERING(2021)
Abstract
Fast access to structurally diverse heteroaromatic compounds is demonstrated in an integrated continuous-flow manner without employing any expensive oxidant. The process involves an electro-flow heating reactor that uses electricity as the green oxidant to promote the reaction, leading to a fast (2 min) annulation reaction for the synthesis of heteroaromatic compounds.
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Key words
Continuous Flow Chemistry,Microfluidics
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