A novel compound bone articular repair material combining deproteinized osteoarticulation with calcium phosphate cement and BMP-9

Calcium phosphate cement loaded with BMP-9 was coated on the surface and partially filled in the intramedullary cavity of deproteinized osteoarticulation. As a novel compound osteoarticular repair material, DPOA/CPC/BMP-9 has excellent biocompatibility, osteoconductivity, osteoinductivity, and angiogenicity, and it is expected to become an excellent alternative repair material for bone tissue engineering.