Cytotoxic effect of cipó-pucá (Cissus sicyoides L.) supercritical extract on human red blood cells and as anti-inflammatory in spinal cord injury in adult rats

Marielba de los Ángeles Rodríguez Salazar, Glides Rafael Olivo Urbina,Vânia Maria Borges Cunha,Fernanda Wariss Figueiredo Bezerra, Michelle Nerissa Coelho Dias, Ijair Rogério Santos,Bruno José Brito Teixeira, Wanessa Almeida Costa,Walace Gomes-Leal, Jesus Nazareno Silva e Souza, Silvia Helena Marques Silva,Raul Nunes Carvalho Junior

The Journal of Supercritical Fluids（2021）

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摘要

•The global yield of C. sicyoides supercritical extract was 3.03 ± 0.10 %.•In C. sicyoides extracts, glycosylated flavonoids were identified by HPLC.•The supercritical extract did not present rupture of red blood cell membranes.•The supercritical extract showed anti-inflammatory effects in the SCI model.

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关键词

Cissus sicyoides L.,Supercritical technology,HPLC,Cytotoxicity,Anti-inflammatory effect

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