N-bromosuccinimide promoted synthesis of β-amino bromides under Appel reaction condition
SYNTHETIC COMMUNICATIONS(2021)
摘要
An efficient and facile method has been developed for the synthesis of chiral β-amino bromides from their corresponding alcohols under Appel reaction conditions. This approach allows for the deoxybromination of a variety of β-amino alcohols in excellent yields under mild conditions without any detectable racemization.
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关键词
N-bromosuccinimide,Nβ-protected amino alcohols,Nβ-protected amino bromides
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