Effectiveness Of Hepatitis C Antiviral Treatment In Attended Patients From The Outpatient Pharmacy Consultation

ARS PHARMACEUTICA(2020)

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摘要
Objective: To determine the effectiveness of the treatment of chronic hepatitis C determined as the sustained viral response at 12 weeks (SVR12) after the end of treatment with direct-acting antiviral drugs (DAA) (glecaprevir/pibrentasvir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voxilaprevir and grazoprevir/elbasvir) in attended patients from the outpatient pharmacy consultation.Method: a retrospective study that includes patients attended by pharmacists who started treatment between December 1, 2017 and May 31, 2018. Demographic data, disease, adherence and treatment consultations were recorded (interactions, adverse effects and others).Results: Two hundred and five patients were included, with different hepatitis C genotypes, fibrosis states and morbidity levels. Effectiveness was 99.5%, similar to that of clinical trials.Conclusions: These results resemble those obtained in pharmacy consultations in the United States, operating for more than ten years.
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关键词
pharmaceutical care, hepatitis C, effectiveness
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