The Study Of Colour Genes Sequences In Chinchilla (Chinchilla Lanigera) Based On Homology Of Human And Mice Sequences

In domesticated animals there are many different coat colors and mutations, often connected with pleiotropic effects. The aim of this thesis named The study of color genes sequences in chinchilla based on homology of human and mice sequences was describe by molecular-genetic principles of pigmentation, introduce genes involved in melanogenesis and influencing a melanin function, their structure, mutations and mention other mutations which change the phenotype. Information about alleles TYR, TYRP1, TYRP2/DCT, agouti, AGRP, gene group MCR gene group (MC1R-MC5R) and more are focused on human (Homo sapiens), mouse (Mus musculus) and chinchilla (Chinchilla lanigera). In these three species selected sequences of genes TYR and TYRP2/DCT were compared.