Wet Dressings With Oxygen-Irrigation Improves Chronic Wound Healing

Objective: To study the advantages and benefits of oxygen-irrigated wound negative pressure in the treatment of chronic wounds. Methods: A total of 76 patients with chronic wounds were enrolled and divided into control and observation groups. The patients in the control group were treated with wet dressings while the patients in the observation group were treated with oxygen-irrigated wound negative pressure along with wet dressings. The wound healing rate, the healing time, and the Pressure Ulcer Scale for Healing (PUSH) scores were compared between the two groups at different times. Results: The wound healing rate in the observation group was significantly higher than it was the control group (P<0.05), and the healing time, total treatment cost, and dressing change frequencies were significantly lower than they were in the control group (all P<0.05). The granulation tissue coverage area in the observation group was significantly higher than it was in the control group (P<0.05) after the treatment, but the PUSH scores, wound area, wound depth, and pH of the exudation were significantly lower (all P<0.05). Conclusions: Oxygen-irrigated wound negative pressure improves the microenvironment in chronic wounds, contributes to the growth of granulation tissue, and improves the wound healing rate.