Study The Relation Between Persistent Chronic Cough And Helicobacter Pylori Infection In Pediatrics Age Group

Introduction: Helicobacter pylori infection is most commonly a cause of gastritis causing symptoms outside gastro intestinal tract. Cough is one of the most common persistent problems in infant and children especially chronic cough with confusing cause. H.p. gastritis spread to nasopharyngeal cavity in case of gastro-esophageal reflux.Aims: To study the correlation in-between Helicobacter pylori gastritis and persistent chronic cough in infant and children.Materials and methods: 2 groups of patients sharing in the study, study group (81) of patients complaining of persistent chronic cough without known cause and control group (41) of patients with persistent chronic cough due to nonspecific laryngeal and pharyngeal infection.Results: Active infection with Helicobacter pylori was found in 88.8 % (72/81) of children of our study group with persistent chronic cough But was 26.8 % (11/41) of our controlled group, supported by presence of the antigen of Helicobacter in the children stool. The difference was apparent significantly shown (p, < 00.001). After treatment by using the proper management for H Pylori there was a significant improving of the persistent chronic cough of 92.8% (65/70) of children (p, 00.001).Conclusions: Persistent chronic cough without recognized cause most commonly due to infection by Helicobacter pylori that leading to laryngeal and pharyngeal inflammation, several manifestations especially persistent chronic cough.