Molecular Microfluidic Bioanalysis: Recent Progress In Preconcentration, Separation, And Detection
ADVANCES IN MICROFLUIDICS - NEW APPLICATIONS IN BIOLOGY, ENERGY, AND MATERIALS SCIENCES(2016)
Abstract
This chapter reviews the state-of-art of microfluidic devices for molecular bioanalysis with a focus on the key functionalities that have to be successfully integrated, such as preconcentration, separation, signal amplification, and detection. The first part focuses on both passive and electrophoretic separation/sorting methods, whereas the second part is devoted to miniaturized biosensors that are integrated in the last stage of the fluidic device.
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Key words
microfluidic bioanalysis, separation, concentration, on-a-chip optical detection, electrochemical sensors
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