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Correlation Of Aortic Stenosis Echocardiographic Parameters In Patients With Normal Ejection Fraction

INSUFICIENCIA CARDIACA(2013)

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摘要
Backround. Echocardiography is the method of choice for evaluating the severity of aortic stenosis, but there are often discrepancies between echocardiographic parameters. The aim of our study was to evaluate the correlation between echocardiographic parameters used to grade the severity of aortic stenosis: aortic valve area (AVA), mean transvalvular gradient (MG) and peak systolic velocity (PV) and assess the discordance between AVA and mean gradient for the diagnosis of severe aortic stenosis.Material and methods. We included consecutively patients who underwent transthoracic echocardiography as part of follow up of aortic stenosis. Was calculated AVA by continuity equation, indexed AVA (iAVA), PV and MG with continuous Doppler. By the method of bivariate correlation was obtained Pearson correlation coefficient between AVA and iAVA-MG, AVA and iAVA-PV. We considered a p<0.05 statistically significant. In addition, the population was divided into 4 groups according to the following echocardiographic parameters, AVA >= 1 cm(2) and <1 cm2; iAVA >= 0.6 cm(2)/m(2) and <0.6 cm(2)/m(2) and GM >= 40 mm Hg and <40 mm Hg.Results. We included 104 patients with a mean AVA of 1.24 +/- 0.40 cm2, a mean iAVA of 0.67 +/- 0.22 cm(2)/m(2), a mean PV of 3.34 +/- 0.89 m/sec and a mean MG of 27.9 +/- 17.6 mm Hg. There was significant correlation between the variables: AVA-MG (correlation coefficient 0.738, p<0.01), AVA-PV (correlation coefficient of 0.801, p<0.01). Remained the same correlation when compared iAVA with MG and PV. Dividing into groups according to valve area and MG, there was discrepancy of echocardiographic parameters of severe aortic stenosis in 12.5% and 17.3%, with AVA or iAVA respectively.Conclusion. Statistical correlation exists between echocardiographic parameters to assess aortic stenosis, but there is disagreement of 12.5 or 17.3%, between AVA or iAVA and mean gradient respectively to assess severe aortic stenosis.
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关键词
Aortic stenosis, Normal ejection fraction, Echocardiographic parameters, Aortic valve area Mean, transvalvular gradient, Peak systolic velocity
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