Development Of Cnt-Polymer Film-Based Electrode For The Detection Of Glucose

Carbon nanotubes (CNTs) have gained considerable attention due to their exceptional properties including high surface area, excellent electrical, mechanical, and thermal properties. Since outer walls of CNTs are chemically inert and hydrophobic in nature, it is of primary importance to make them compatible for their use. Among various methods, oxidation of CNTs surfaces by simple acids provides a mean to immobilize biomolecules and new surfaces. Protein-CNT conjugates are being developed for a wide range of biomedical devices and therapies including drug delivery, cancer therapy, and biosensing applications. The ability of CNTs to promote electron transfer in various redox reactions suggests great promise for oxidases-based amperometric biosensor and this has led to the development of electrode modified with CNTs in the application of electrocatalytic oxidation of glucose, uric acid, cytochromec, nitric oxide, 4-aminophenol etc. Here our study presents the application of functionalized CNT for electro-conductive filmmaking using simple fabrication method. The fabricated CNT film has been used to study the immobilization of enzyme and its application as glucose biosensor. We have studied the surface morphology of CNT film by transmission electron microscopy (IBM) and Fourier-transform infrared (FTIR) spectrometer while the biosensor/ bioelectronic properties of the CNT film-based electrode was studied by bio-electrochemical techniques like cyclic voltammetry. The results suggest that CNT-polymer-based film can uniformly disperse the functionalized CNTs by molding methods which were found to be suitable for preparing transducers and it can be used for the measurement of glucose in an aqueous system.