Synthesis Of 1,5-Dideoxy-3-O-(Alpha-D-Mannopyranosyl)-1,5-Imino-D-Mannitol And 1,5-Dideoxy-3-O-(Alpha-D-Glucopyranosyl)-1,5-Imino-D-Mannitol - Powerful Inhibitors Of Endomannosidase
TETRAHEDRON-ASYMMETRY(1993)
摘要
The synthesis and conformations of 3-O-methylDMJ, 3-O-(alpha-D-glucopyranosyl)-DMJ (Glcalpha1,3DMJ), and 3-O-(alpha-D-mannopyranosyl)-DMJ (Manalpha1,3DMJ) are described. Manalpha1,3DMJ and Glcalpha1,3DMJ are shown to be very powerful inhibitors of an endomannosidase. The potential use of these compounds in both probing the pathways of N-linked glycoprotein processing and in the chemotherapy of some viral diseases is discussed.
更多查看译文
关键词
powerful inhibitors,synthesis,d-mannopyranosyl,imino-d-mannitol,d-glucopyranosyl
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要