Inhibition Of Oxidative Stress In Vivo Through Enzyme-Like Activity Of Carbon Dots

Oxidative stress is a huge challenge to human health, and effective agents for resisting this adverse ef-fect are remains limited recently. Here, an excellent enzyme-like activity of carbon dots (e-CDs) via a facile solvothermal method is reported. In addition, e-CDs exert protective effects in HUVEC cell model by decreasing apoptosis. e-CDs also efficiently diminish ROS and apoptosis damage in mice treated with D-galactose. Furthermore, e-CDs-pretreated mice shows decrease apoptotic proteins in the brain and liver, confirming that e-CDs ameliorate D-galactose induced aging. Compared with general nanozymes, biocom-patible e-CDs demonstrate their high potential for anti-aging by the inhibition of oxidative stress. (c) 2021 Elsevier Ltd. All rights reserved.