Solubility Behavior Of N-Carbobenzoxy-L-2-Phenylglycine In 11 Pure And A Binary Ethanol Plus Water Solvent Systems At 283.15-323.15 K

The mole fraction solubility data of N-carboxyphenoxy-L-2-phenylglycine in 11 neat solvents (methanol, water, isopropyl alcohol, ethanol, n-propyl alcohol, methyl acetate, ethyl acetate, acetone, dichloromethane, acetonitrile, and butanone) and a binary solvent mixture of ethanol + water were determined by the static gravimetric method at 283.15-323.15 K. From the solvent effect analysis, the solubility behavior was affected not only by polarity, but also by some other factors such as hydrogen bonding, cohesive energy density, and molecular structure. The solubility data of N-carboxyphenoxy-L-2-phenylglycine were correlated by using the two-dimensional modified Apelblat model and three-dimensional Apelblat-Jouyban - Acree model. The maximum values of root-mean-square deviation and relative average deviation were 100.98 x 10(-4) and 20.53%, respectively. The solubility calculated by the two models agreed well with the experimental values.