Correlation Between Genomic Alterations And Germline Mutations In Men With Metastatic Castration-Resistant Prostate Cancer (Mcrpc)

C. Llacer Perez,L. Oliva Fernandez, E. Canada-Higueras,M. I. Saez,R. Villatoro,A. Montesa Pino,B. Herrera Imbroda,D. Hernandez,R. Lozano Mejorada,N. Romero Laorden,M. Marquez,G. Grau,A. Pineda,F. J. Lopez, P. Peinado,D. Alameda,D. Olmos,E. Castro

ANNALS OF ONCOLOGY（2021）

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摘要

Germline testing is advised for all metastatic prostate cancer patients (pts) and particularly for those with alterations in cancer-predisposition genes found through tumor profiling. To date, no patient or tumor characteristics have been unequivocally correlated with germline mutations to assist clinicians in prioritizing genetic testing.

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关键词

prostate cancer,germline mutations,genomic alterations,castration-resistant

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