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Insula Functional Connectivity During Urge Suppression In Obsessive-Compulsive Disorder

Goi Khia Eng,Katherine Collins,Laura Bragdon,Amanda Belanger,Maya Charan,Russell H. Tobe,Lazar Fleysher,Dan V. Iosifescu,Emily R. Stern

BIOLOGICAL PSYCHIATRY（2021）

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Abstract
Individuals with obsessive-compulsive disorder (OCD) often report urges preceding their compulsions. Although the insula has a key role in interoception and prior work in OCD showed increased neural activity during the build-up of an urge using an eyeblink-suppression task, little is known about insula connectivity during urge-suppression in OCD.
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Key words
Obsessive Compulsive Disorder (OCD), Insula, Functional Connectivity, Urge Suppression, Interoception
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