Reported Experiences Of Childhood Trauma Does Not Explain Altered Brain Network Integration Or Segregation Detected In Schizophrenia

Structural brain alterations in both grey and white-matter regions are more pronounced among individuals with schizophrenia with reported experiences of childhood-trauma (CT).Examining the topological arrangement of connections encompassing both grey and white-matter is key to understanding the role of CT on structural brain network architecture and at a network level may be more informative for examining the mechanisms underlying the additive effects of CT in schizophrenia.