Effect of Chronic Kidney Disease on Taste Function: A Case Control Study among Nigerian

INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY(2021)

引用 1|浏览8
暂无评分
摘要
Taste dysfunction has been associated with chronic kidney disease (CKD) especially end stage kidney disease (ESKD) and also implicated as one of the predisposing factors for the prevalent malnutrition, muscle wasting and impaired quality of life among patients with CKD. To assess the taste function and determine the pattern of taste dysfunction in patients with CKD attending the University College Hospital, Ibadan. This was a cross sectional, hospital-based case–control study of adult patients with CKD. The control group were age and sex matched without CKD. Interviewer-assisted questionnaires were administered on all participants to obtain clinical information concerning demographics, clinical data on kidney disease and taste dysfunction. The four basic taste modalities namely; sweet, sour, bitter and salt taste senses of the participants were tested with validated “taste strips”. There were 100 patients with CKD and 100 healthy controls, age ranges between 19 and 86 years (mean ± SD = 46.3 ± 13.9 years) and 20 and 85 years (mean ± SD = 43.4 ± 14.9 years), respectively. There was no statistically significant difference between cases and control gender distribution ( p = 0.57). Hypogeusia was found in 27.0% of CKD patients with specific taste modalities dysfunction for salt, sour, sweet and bitter taste of 13.0, 24.0, 13.0 and 17.0%, respectively. The controls only had specific taste modalities dysfunction for salt, sour and bitter taste of 1.0% for each of the taste modalities. The mean total taste scores in the cases and controls were − 9.8 ± 3.2 and 13.4 ± 1.5 ( p = 0.001), respectively. The mean taste scores were significantly lower among the cases than controls, salt taste-2.82 ± 1.1 and 3.7 ± 0.7 ( p = 0.001), sour taste − 2.2 ± 1.0 and 3.2 ± 0.7 ( p = 0.001), sweet taste-, 2.9 ± 1.8 and 3.8 ± 0.5 ( p = 0.001), bitter taste − 1.9 ± 1.2 and 2.8 ± 0.9 ( p = 0.001). Taste dysfunction is prevalent among patients with CKD and the affectation involves all taste modalities.
更多
查看译文
关键词
Taste dysfunction, Chronic kidney disease, Taste strip, Taste modalities
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要