Forniceal Glioma In Children

Object Five to ten percent of pediatric brain tumors are located to the ventricles. Among them, forniceal lesions are rare and their management has not often been described. The aim of this study seas to review the clinical, radiological. and histopathological features as well its the feasibility of surgical excision and the outcomes in these patients.Methods From a retrospective analysis of 250 cases of supratentorial pediatric glioma. the records of 8 children presenting with forniceal lesions were selected and reviewed.Results. The median age of patients to the cohort was 13.5 years Presenting features included intracramal hypertension (7 cases). hypothalamic dysfunction (2). and memory dysfunction (3) Complete resection was possible in only I case. where the lesion was mainly exophytic. the remaining patients had either a partial resection or biopsy On histological review. the tumors were confirmed as pilocytic astrocytoma (4 lesions), WHO Grade 11 astrocytoma (3), and ganghoghoma (1) Postoperatively. working and retrograde memory was normal for all patients, but the authors found a mild alteration in verbal episodic memory in 5 patients. Despite fatigability for 5 patients, academic achievement was normal for all but 2. both of whom had preoperative school difficulties Additional treatment was required for 5 patient; for tumor progression. with a median interval of 19 months from surgery At a median follow-tip duration of 4 9 years. all patients had stable disease.Conclusions. In this series. forniceal glimas were found to be low-grade gliomas. They :ire surgically challenging. and only exophytic lesions may be cured surgically Due to the high rate of progression of residual disease, adjuvant therapy is recommended for infiltrative tumors. and it yielded excellent results (DOI 10.3171/2009.4.PEDS08472)