Low Selenium And Reduced Cognitive Function In A Cohort Elderly Study

NEURAL REGENERATION RESEARCH(2010)

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Abstract
Cognitive function in the elderly is affected by various environmental, social, and individual factors. Studies show that chemical trace elements are closely related to cognitive function. As a protective factor, selenium promotes cognition in the elderly. However, study results into the effects of selenium on cognition have varied. By eliminating unstable environmental and other related factors, the present study selected elderly individuals from rural areas of the Shandong province to verify whether low selenium exposure is a risk factor for decreased cognitive function. Results demonstrated that age, sex, education, occupation, hypertension, stroke, and body selenium levels were factors affecting cognitive function in the elderly, and that selenium was an important protective factor. Moreover, results supported the hypothesis that a lifelong low selenium level is associated with low cognitive function.
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Key words
elderly, rural areas, cognitive function, influential factors, selenium level, Alzheimer's disease, epidemiology, cohort study
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