LB790 Toward new depigmenting agents through drug repurposing: Melanogenesis inhibition by para-aminophenols

Inhibitors of the enzyme tyrosinase have found clinical utility as agents to treat disorderrs of hyperpigmentation. Potential toxicity and carcinogenicity of currently approved depigmenting agents motivates the discovery of safer and more effective alternatives. We report the identification and characterization of tyrosinase inhibitors that are