Therapeutic Drug Monitoring: The Way Towards Individualized Secukinumab Dosing In Psoriasis
JOURNAL OF INVESTIGATIVE DERMATOLOGY(2021)
Abstract
With the introduction of new biologics for psoriasis, achieving optimal response is a realistic goal. However, real life data reveal that response varies from optimal to non-response and loss of response urging physicians to explore off-label intensification. Therapeutic drug monitoring (TDM) could prevent these 'blind' modifications by guiding physicians in their clinical decision-making. In order to perform TDM, two fundamental requirements are 1) assay accessibility and 2) knowledge about an optimal therapeutic window.
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Key words
psoriasis,individualized secukinumab,therapeutic drug monitoring
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