PBAT hollow porous microfibers prepared via electrospinning and their functionalization for potential peptide release

•Polybutylene adipate terephthalate hollow porous microfibers (HPMFs) are prepared.•The loading capacity of polypeptide on HPMFs is improved compared with on MFs.•The inhibition rates of RGD@HPMFs on HeLa and A549 are higher than RGD@HPMFs by 14.1% and 6.9%, respectively.•Controlled loading and sustained release of polypeptide challenges are addressed.