Alpha-glucosidase and tyrosinase inhibiton of polyphenols isolated from Potentilla speciosa var. speciosa: In vitro and in silico perspectives
Industrial Crops and Products(2021)
Abstract
•A number of extracts and isolates of Potentilla speciosa var. speciosa were identified.•The extracts and isolates were tested for α-glucosidase and tyrosinase inhibition.•The butanol extract and Cinnamtannin D1 proved highly potent α-glucosidase inhibitors.•It is the first report of Cinnamtannin D1 occurrence in genus Potentilla.•Molecular docking suggested allosteric binding for Cinnamtannin D1.
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Key words
Cinnamtannin D1,Potentilla,Rosaceae,Molecular modelling
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