Treatment Sequences And Prognostic Factors In Metastatic Pancreatic Ductal Adenocarcinoma: Univariate And Multivariate Analyses Of A Real-World Study In Europe

Real-world data on treatment patterns/outcomes for metastatic pancreatic cancer (mPAC) are limited. This study aims to assess real-world treatment patterns, survival outcomes, and prognostic/predictive factors in patients with mPAC. Retrospective, observational, chart-review involving medical oncologists and gastroenterologists from five European countries. Physicians reported information on disease and patient characteristics, diagnosis, and treatment for patients diagnosed with mPAC from January-October 2016. Outcomes included median progression-free survival (mPFS), median overall survival (mOS), and the impact of baseline performance status on survival. Univariate/multivariate regression analyses were undertaken to identify prognostic/predictive factors. Three hundred four physicians and 3432 patients were included. First-line therapies included modified (m)FOLFIRINOX (28.4