Black Chokeberry (Aronia Melanocarpa) Extracts In Terms Of Geroprotector Criteria

Background: Black chokeberry (Aronia melanocarpa (Micht.) Elliot) is a great dietary source of a wide range of biologically active compounds, such as anthocyanins, flavonoids, other phenolic compounds, vitamins, and minerals that have a wide range of health benefits. Scope and approach: Here we provide an overview of the in vitro and in vivo effects of A. melanocarpa extracts to reveal its potential anti-aging properties in terms of meeting the criteria for a geroprotector. The possible mechanisms of the anti-aging action of black chokeberry extracts are highlighted. Key findings and conclusions: A. melanocarpa extract exhibit geroprotective activity like lifespan extension, antiproliferative activity, improvement of glucose and lipid metabolism, amelioration of neurodegenerative disorders, antiviral and antibacterial activity, protection of the gastrointestinal system. The mechanisms of A. melanocarpa anti-aging action may be associated with the hormesis effect, activation of antioxidant-defense, modulation of insulin/IGF-1 signaling, and anti-inflammatory activity.