Oral Preneoplasia And Neoplasia - Clinical Risk Profile

The aim of the paper was to create a model of clinical profile of the patients at risk of developing oral preneoplasia and neoplasia (OPN). For the purpose, 232 oral lesions (OL) of patients were studied, as the main highlights in the assessment of the clinical profile of the patient at risk of developing OPN were: gender, age, presence of systemic diseases, medications, harmful habits (parafunctions), presence of prostheses, etc. The values of the risks (OR), indicating the malignant potential of the available OL, were divided into three degrees: mild - OR > 1 to 3, medium - OR > 3.1 to 5 and high - OR > 5.1. The results showed that the mean male age was 55.78 +/- 16.245 years; women - 54.41 +/- 12.56 g. The presence of dry mouth, allergies, systemic diseases or systemic use of drugs were reported with a higher frequency in cases of OPN. The cases under 50 years of age using medication or with systemic diseases were 3 to 4 times higher. The use of drugs in patients over 65 years is associated with a higher percentage of cases of OPN - 3 (42.9%) than those studied with other OL - 7 (22.6%). In both age groups (under and over 65 years), systemic diseases are also more common in patients with OPN. It was found that in patients under 50, the presence of: dry mouth, allergies, systemic diseases and systemic medication, increases the risk of existing OL to be malignant by three to more than five times. Patients over 65 years of age with OL, with gum problems (OR - 9.000) and dry mouth (OR - 8.571) have the highest risk of malignancy.