Kaempferol prevents the progression from simple steatosis to non-alcoholic steatohepatitis by inhibiting the NF-κB pathway in oleic acid-induced HepG2 cells and high-fat diet-induced rats

•Kaempferol prevents the development of NAFLD.•Kaempferol potentially suppresses inflammatory responses.•Kaempferol inhibits the nuclear transcriptional activity of NF-κB.•Kaempferol prevents the development of NAFLD by targeting multiple targets.