Immunomodulatory activity of polysaccharide from Arca granosa Linnaeus via TLR4/MyD88/NFκB and TLR4/TRIF signaling pathways

Lijun Zhu, Wei Li,Ziying Fan,Xianying Ye,Ruyi Lin,Mengmeng Ban,Lingzhi Ren,Xiaoqing Chen,Danyan Zhang

Journal of Functional Foods（2021）

引用 10|浏览6

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摘要

•Polysaccharide from Arca granosa Linnaeus can active RAW264.7 cells.•Toll-like receptor 4 is the receptor for the immunomodulatory activity of Polysaccharide from Arca granosa Linnaeus.•Polysaccharide from Arca granosa Linnaeus can activate TLR4/MyD88/NFKB and TLR4/TRIF signaling pathways.

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关键词

Polysaccharide from Arca granosa Linnaeus,Immunomodulatory ability,Mechanism

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