Synthesis Of Spirooxindoles Bearing 1,3-Oxathiolane-2-Thione Moiety From Isatin-Derived Propargylic Alcohols
BULLETIN OF THE KOREAN CHEMICAL SOCIETY(2021)
Abstract
Spirooxindoles bearing 1,3-oxathiolane-2-thione moiety were synthesized from isatin-derived propargylic alcohols and carbon disulfide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). The spirooxindoles were formed stereoselectively via attack of the alkoxide of propargylic alcohol to carbon disulfide to form xanthate anion and a following 5-exo-dig cyclization process.
MoreTranslated text
Key words
Spirooxindoles, 1,3-Oxathiolane-2-thione, Isatin-derived propargylic alcohols, Carbon disulfide
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined