Efficacy, Pharmacokinetics, And Tolerability Of Subcutaneous Secukinumab Injections With 2 Ml Prefilled Syringes (300 Mg) In Adult Subjects With Moderate To Severe Plaque Psoriasis

Bardur Sigurgeirsson,Knut Schaekel,Chih-Ho Hong,Isaak Effendy,Waldemar Placek,Phoebe Rich,Gerard Bruin,Pascal Charef,Rong Fu,Isabelle Hampele,Manmath Patekar

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY（2021）

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摘要

Introduction: Evidence shows good tolerability in patients receiving subcutaneous injection volumes up to 3 mL. The ALLURE study investigated efficacy, pharmacokinetics, and tolerability of secukinumab 300 mg 2 mL prefilled syringe (PFS).

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subcutaneous secukinumab injections,severe plaque psoriasis,pharmacokinetics

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