Synthesis, Characterization And Biological Activity Of Some Novel Benzimidazole Linked 1,3,4-Oxadiazoles

Novel benzimidazole derivatives in combination with 1,3,4-oxadiazoles (4a-o) were synthesized from ethyl 3-((5-chloro-2-nitro phenyl)(phenyl)amino)-3 oxo propanoate (1) via three step synthetic strategy and tested for their antimicrobial activity. The newly synthesized compounds (4a-o) were characterized by (HNMR)-H-1, IR and Mass spectral data. Compounds 4l and 4m showed significant antibacterial activity with tested bacterial pathogens (E.Coli, B.subtilis).