Analyze Of Intra-Cystic Fluid Of Bosniak Iii-Iv Renal Lesions: Does It Contain Tumoral Cells?

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy II (PD16)1 Sep 2021PD16-08 ANALYZE OF INTRA-CYSTIC FLUID OF BOSNIAK III-IV RENAL LESIONS: DOES IT CONTAIN TUMORAL CELLS? Julien Anract, Charles Dariane, Antoine Soutif, Virginie Verkarre, Francois Audenet, Sophie Hurel, Jean Michel Correas, Marc Olivier Timsit, and Arnaud Mejean Julien AnractJulien Anract More articles by this author , Charles DarianeCharles Dariane More articles by this author , Antoine SoutifAntoine Soutif More articles by this author , Virginie VerkarreVirginie Verkarre More articles by this author , Francois AudenetFrancois Audenet More articles by this author , Sophie HurelSophie Hurel More articles by this author , Jean Michel CorreasJean Michel Correas More articles by this author , Marc Olivier TimsitMarc Olivier Timsit More articles by this author , and Arnaud MejeanArnaud Mejean More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001998.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Surgical ablation of Bosniak III-IV renal cysts is the standard of care. There is a theoretical risk of tumoral spillage in case of cyst rupture, even if no impact on recurrence free survival has been demonstrated. The aim of our study was to analyze the cellularity of intra-cystic fluid, to asses if it can contain tumoral cells. METHODS: All patients who underwent surgical management of a Bosniak III or IV cystic renal lesion between January 2018 and January 2019 in our center were prospectively included. The intra-cystic fluid was punctured in the operating room, after extraction of the renal tumor. The punctured fluid underwent centrifugation and direct cytological analysis. RESULTS: Intra-cystic fluid were punctured and analyzed in 31 patients. Twenty-three (74.2%) of the cysts were Bosniak IV. Twenty-four (77.4%) of the cysts were malignant according to the final histological analysis. We found tumoral cells in one (3.2%) intra-cystic fluid. 28 (93.3%) intra-cystic fluids contained inflammatory cells, and 2 (6.7%) were acellular. CONCLUSIONS: Our results suggest that renal cysts can exceptionally contain tumoral cells. Even if there is no impact demonstrated of a cyst rupture on recurrence free survival, the surgery should be conducted with maximum of precautions to avoid cyst rupture. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e281-e281 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Julien Anract More articles by this author Charles Dariane More articles by this author Antoine Soutif More articles by this author Virginie Verkarre More articles by this author Francois Audenet More articles by this author Sophie Hurel More articles by this author Jean Michel Correas More articles by this author Marc Olivier Timsit More articles by this author Arnaud Mejean More articles by this author Expand All Advertisement Loading ...