Ten Years Of Experience In The Non-Intensive Treatment Of Acute Leukemias In Elderly Patients Of The Hematology Service Of The National Medical Center November 20, Issste

Leukemia is a malignant hematological disease in which excessive clonal proliferation, deregulation, and altered differentiation of hematopoietic stem cells can occur, affecting bone marrow, peripheral blood and other tissues. Advanced age is considered an adverse prognostic factor, even after taking into account other risk factors such as cytogenetics, molecular genetics, type of acute leukemia and the patients' physical state. In elderly patients with or without treatment, the prognosis is poor, with a median estimated survival of two months and only 6% survival at two years.