ID: 3526904 PRIMARY OBESITY SURGERY ENDOLUMINAL 2 (POSE 2.0): AN INTERNATIONAL MULTICENTER PROSPECTIVE TRIAL WITH PLICATION DURABILITY ASSESSMENT

Gastric endoscopic bariatric and metabolic therapies (EBMTs) that remodel the stomach offers durable alternative to temporary removable space-occupying EBMTs. The Primary Obesity Surgical Endoluminal 2 (POSE2) procedure, performed using the Incisionless Operating Platform (IOP) (USGI, San Clemente, CA), involves a new pattern of full-thickness gastric plications with durable suture anchor pairs that both shortens and tabularizes the greater curvature of the stomach (figure 1). This international, protocol-driven, prospective multicenter trial examined the safety, efficacy, and durability of the POSE2 procedure.