Copper Concentrations In Obese Women And Their Relationship To Lipid Peroxidation Marker

Background: Current studies have shown a relationship between antioxidant minerals and biochemical disorders involved in the pathogenesis of obesity, especially lipid peroxidation. In this sense, the literature reveals importance of the performance of trace elements, such as copper, in the protection against the excessive production of free radicals in obese individuals.Objective: was to evaluate how the associations of obese women and their interface with lipid peroxidation.Methods: Cross-sectional, analytical and experimental involved 89 women, aged between 20 and 50 years, divided into two groups: control group (eutrophic women, n = 45) and case group (obese, n = 44). As plasma and erythrocyte concentrations of copper and determined by atomic absorption spectrometry. Plasma concentrations of TBARS were determined following the method described by Ohkawa, Ohishi and Yagi (1979), with adaptations.Results: The concentration of the reactive substances to thiobarbituric acid was significantly higher in the case group compared to the control group (p = 0,001). The case group had lower concentrations of plasma and erythrocyte copper (p < 0,05). Both groups had adequate concentrations of erythrocyte and plasma copper. There was no significant correlation between plasma and erythrocyte copper and adiposity parameters (p> 0,05).Conclusion: From the results of this study, it can be concluded that the participants of the study have plasma and erythrocyte copper concentrations within the adequacy range, and the case group presents lower concentrations compared to the control group. In addition, no significant correlation was found between the lipid peroxidation marker and the plasma and erythrocyte copper concentrations.