Direct Cross-Coupling Of Alcohols With O-Nucleophiles Mediated By N-Iodosuccinimide As A Precatalyst Under Mild Reaction Conditions
CATALYSTS(2021)
摘要
We report N-iodosuccinimide as the most efficient and selective precatalyst among the N-halosuccinimides for dehydrative O-alkylation reactions between various alcohols under high-substrate concentration reaction conditions. The protocol is non-metal, one-pot, selective, and easily scalable, with excellent yields; enhancing the green chemical profiles of these transformations.
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关键词
alcohols, N-iodosuccinimide, cross-coupling, etherification, green chemistry
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