Favorable Outcome Of Sequential Hla-Haploidentical Transplantation Using Ptcy As Gvhd Prophylaxis In High Risk Aml And Mds Of The Elderly

BLOOD(2018)

Cited 2|Views10
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Abstract
Sequential conditioning regimens, comprising cytoreductive chemotherapy shortly applied prior to reduced intensity conditioning are successfully used for high-risk (HR) AML/MDS in matched related and unrelated donor hematopoietic stem cell transplantation. However, few data are available for sequential conditioning in the context of HLA-haploidentical transplantation (haplo-HSCT), especially in the elderly. To investigate the relative merits of sequential haplo-HSCT in the elderly we retrospectively analyzed the outcome of thirty-five patients (pts) with advanced AML/MDS (>=50 years old).
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Key words
gvhd prophylaxis,transplantation,hla-haploidentical
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