Automated Functional Analysis Of Cellular Lipid Metabolism Provides Insights Into The Variability Of Hypercholesterolemia In Individual Patients

S. Pfisterer, I. I. C. Brock,I. Hlushchenko,K. Kanerva,M. M. Islam,P. Ripatti,L. Paavolainen,J. Kuusisto,P. Horvath,S. Ripatti,M. Laakso,E. Ikonen

ATHEROSCLEROSIS（2021）

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摘要

Background and Aims: Hypercholesterolemia evolves very differently in individual patients, depending in part on lifestyle and genetic risk factors. However, to which extent cellular functions influence the development of hypercholesterolemia, and how they might differ from patient to patient, remains poorly defined.

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关键词

hypercholesterolemia,cellular lipid metabolism,lipid metabolism,automated functional analysis

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