Efficient Synthesis Of Pyrazinoic Acid Hybrid Conjugates

Siva S. Panda,Abdullah M. Asiri,Mohamed Elagawany, Devan D. Buchanan, Behrad Torkian, Keerthana Bathala,Sean J. Thomas,Jason E. Capito,Muhammad N. Arshad,Abeer N. Ai-Romaizan

SYNOPEN（2017）

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摘要

Benzotriazole-activated pyrazinoic acid was utilized as a versatile building block for the efficient and convenient synthesis of novel hybrid conjugates of pyrazinoic acid with secondary amines via amino acid linkers in high yields.

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关键词

pyrazinamide, pyrazinoic acid, secondary amines, amino acids, benzotriazole methodology, antituberculosis

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