Rapid Discrimination Of Fritillary Herbs By A Photochemical Colorimetric Sensor Array

Fritillaria is a kind of traditional Chinese medicine commonly used in China. Fritillaria has the effect of relieving cough and reducing phlegm, but its curative effect and price are quite different. In the market, the confusion and adulteration of Fritillaria medicinal materials are very common, the traditional character identification and microscopic identification cannot meet the actual needs, and the modern identification methods generally have the limitations of long analysis time, high instrument requirements, and high price. This work was based on the organic acids and nucleosides in Fritillaria, with the help of two color development principles, "indicator displacement" and "changes in pH", using commercial indicators with cross-response to build a 3x3 photochemical colorimetric sensor array for rapid identification of Fritillaria medicinal materials. The sensor array had different color change patterns in different fritillary herbs, which constituted the unique fingerprint of fritillary herbs. Partial least square discriminant analysis (PLS-DA) was used for distinguishing and identifying Chuanbeimu, Hubeibeimu, Pingbeimu, Yibeimu, Zhebeimu, fake Fritillaria, so as to realize the accurate and rapid distinguishing of Fritillaria. This work provided a simple and cost-effective method for the rapid identification and quality control of Fritillaria.