Synthesis of 5-(hydroxy-, chloro-, bromomethyl)furan-2-enones Based on Fructose and their Antioxidant Activity
CHEMISTRY OF NATURAL COMPOUNDS(2021)
Abstract
New enones were synthesized from 5-hydroxymethylfurfurol (5-HMF) and its derivatives using Wittig reactions of various phosphoranes. The synthesized enones were observed to affect free-radical oxidation in model systems, in particular, to suppress generation of reactive oxygen species.
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Key words
5-hydroxymethylfurfurol,phosphorus ylides,Wittig reaction,phosphoranes,imides,enones,antioxidant activity
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