Gender differences and risk factors for acute kidney injury following cardiac surgery: A single center retrospective cohort study

Background: We studied AKI incidence and prognosis in cardiac surgery patients under and over 60 years old.Methods: We studied AKI in patients who underwent cardiac surgery at the First Affiliated Hospital of Wenzhou Medical University between Jan 2020 and Dec 2021, using improved global prognostic criteria for diagnosis.Results: After analyzing 781 patients (402 males, 379 females), AKI incidence after surgery was 30.22 %. Adjusting for propensity scores revealed no significant difference in AKI incidence between young males (24.1 %) and females (19.3 %). However, young females had higher AKI stages. Among older patients, AKI incidence was comparable between males (43.4 %) and females (42.2 %), but females had longer intubation times. Independent risk factors for AKI included age, male gender, and BMI, while intraoperative hemoglobin level was protective.Conclusions: No gender gap in AKI frequency for <60 years old and >= 60 years old post-cardiac surgery, yet women display increased AKI severity and extended intubation duration.