Stent Thrombosis After Primary Percutaneous Coronary Intervention In Real World Patients

From January 2006 to May 2011, 2018 patients with ST-segment elevation myocardial infarction (STEMI) underwent primary percutaneous coronary intervention (PCI) at our institution. Stenting was performed in 87% of patients and a total of 1950 (75%) bare-metal stents (BMS) and 638 (25%) drug-eluting stents (DES) were implanted. At follow-up (median 34 months) definite stent thrombosis occurred in 2.3% of stented patients: 8 acute (0.46%), 22 subacute (1.25%), 5 late (0.28%), and 6 very late (0.34%). Thrombosis occurred in 1.6% of stents implanted (1.7% of BMS vs. 1.1% of DES; p = 0.17). Multivariate logistic regression analysis revealed Killip class at admission, number of stents deployed in infarct-related artery, left anterior descending artery and non-use of IIb/IIIa inhibitors to be independent predictors of stent thrombosis at follow-up.