Surgical Treatment Of Duodenal Gists

GISTs (gastrointestinal stromal tumours) are neoplasias of the gastrointestinal tract and represent a relatively new nosological entity, which has been increasing over the last 10 years, and now represents about 1-5 % of all neoplasias. At immunohistochemical analysis, positivity for CD 117 is mandatory in order to make a differential diagnosis from all the other tumours of mesenchymal origin. Their location varies, interesting all the gastrointestinal tract with different percentages; duodenal location is in the order of 3-5%. There are various parameters to define the degree of malignancy, even if, in all cases, the only possibility of recovery is complete surgical resection. Even though extensive lymphadenectomy is not necessary, because they metastasize through the bloodstream, duodenal GISTs are tumours that present notable difficulties for the therapeutic approach, in relation to the site of onset, the type of surgical resection, and because of elevated mortality and post-operative complications.