Moth-Eaten - Immunodeficient Mouse With Markedly Less Ability To Survive Than Nude Mouse In A Germfree Environment

Summary The motheaten mouse is an immunodeficient mutant which has been found to have elevated immunoglobulin levels, to exhibit autoimmunity, and early death. Since survival is not improved by a germfree environment, it appears that some mechanism other than infection results in its early demise.